Facile Synthesis of 6-Aryl-3-cyanopyridine-2-(1 H)-thiones from Aryl Ketones

RL Zheng, XX Zeng, HY He, J He, SY Yang…

Index: Zheng, Ren-Lin; Zeng, Xiu-Xiu; He, Hai-Yun; He, Jun; Yang, Sheng-Yong; Yu, Luo-Ting; Yang, Li Synthetic Communications, 2012 , vol. 42, # 10 p. 1521 - 1531

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Abstract

3-Cyanopyridine-2-(1H)-thiones are valuable compounds in organic synthesis not only because of their broad biological activities [ 1 1. For representative papers, see (a) Litvinov , VP ; Dotsenko , VV ; Krivokolysko , SG Thienopyridines: Synthesis, properties, and biological activity . Russ. Chem. Bull. 2005 , 54 , 864 – 904 ; (b) Krauze , A. ; Gērmane , S. ; Eberlinš , O. ; Šturms , I. ; Klusā , V. ; Duburs , G. Derivatives of 3-cyano-6-phenyl-4-(3'-pyridyl)-pyridine-2(1H)-thione and ...