A new manifold for the Morita reaction: diene synthesis from simple aldehydes and acrylates/acrylonitrile mediated by phosphines

A Palmelund, EL Myers, LR Tai, S Tisserand…

Index: Palmelund, Anders; Myers, Eddie L.; Tai, Lik Ren; Tisserand, Steve; Butts, Craig P.; Aggarwal, Varinder K. Chemical Communications, 2007 , # 40 p. 4128 - 4130

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Citation Number: 7

Abstract

The mechanism of the amine catalysed reaction is well understood and the importance of the requisite proton transfer event (1,3-proton transfer), established as the RDS, has been highlighted in our laboratory and that of McQuade. 7 Recently, DFT calculations on the phosphine catalysed variant support the same RDS and a fully and more rapidly reversible reaction (compared to amines ). 8 However, it is observed that, whilst amines are the catalyst of choice for most ...