e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Journal of fluorine chemistry
2-hydryl-2-(F-methyl)-F-propanoyl fluoride as a useful building block for the synthesis of trifluoromethylated heterocyclic compounds. Synthesis of 1, 3-dimethyl-2, 3- …
Y Inouye, T Yokozawa, N Ishikawa
Index: Inouye, Yoshio; Yokozawa, Tsutomu; Ishikawa, Nobuo Journal of Fluorine Chemistry, 1985 , vol. 27, p. 379 - 384
Abstract The usefulness of 2-hydryl-2-(F-methyl)-F-propanoyl fluoride as a building block for the synthesis of trifluoro methylated compounds has been shown in the synthesis of the title compounds by the reaction of the acid fluoride with 1, 3-dimethylthiourea and 1, 3- dimethylurea followed by intramolecular cyclization.
