Abstract New indolyloxypropanolamines in which the substituent at the side chain nitrogen atom was the 2-(1H-indol-3yl)-1, 1-dimethylethyl group have been synthesized as putative anti-hypertensive agents. In vitro assays were used to measure their affinity for the β 1-, β 2, α 1-and α 2-adrenoceptors, where a marked tendency towards β 2-adrenoceptor selectivity was observed.
