e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron Letters

Palladium assisted synthesis of 1-azaspirocycles

…, JD Meinhart, DJ Miller, S Van Wallendael

Index: Godleski, Stephen A.; Meinhart, James D.; Miller, David J.; Wallendael, Shawn Van Tetrahedron Letters, 1981 , vol. 22, # 24 p. 2247 - 2250

Full Text: HTML

Citation Number: 33

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A facile, general route to 1-azaspirocycles utilizing a π-allyl palladium complex in the key cyclization step has been developed. ... Accounts of this work have been presented at the following meetings 179th National ACS Meeting, Houston, Texas, March 1980, “Palladium Catalyzed ...

3-(4-(benzylamino)butyl)cyclohex-2-en-1-yl acetate Structure

3-(4-(benzylami...

~93%

3-(4-hydroxybutyl)cyclohex-2-enone Structure

3-(4-hydroxybut...

3-(4-hydroxybutyl)-2-cyclohexen-1-one Structure

3-(4-hydroxybut...

~%

3-(4-hydroxybutyl)cyclohex-2-enone Structure

3-(4-hydroxybut...

4-(3-hydroxycyclohex-1-en-1-yl)butyl 4-methylbenzenesulfonate Structure

4-(3-hydroxycyc...

~%

3-(4-hydroxybutyl)cyclohex-2-enone Structure

3-(4-hydroxybut...

4-(3-oxocyclohex-1-en-1-yl)butyl 4-methylbenzenesulfonate Structure

4-(3-oxocyclohe...

~%

3-(4-hydroxybutyl)cyclohex-2-enone Structure

3-(4-hydroxybut...

3-(4-(tosyloxy)butyl)cyclohex-2-en-1-yl acetate Structure

3-(4-(tosyloxy)...

~%

3-(4-hydroxybutyl)cyclohex-2-enone Structure

3-(4-hydroxybut...

3-(3-(benzylamino)propyl)cyclohex-2-en-1-yl acetate Structure

3-(3-(benzylami...

~99%

1-benzyl-1-azaspiro[4.5]dec-6-ene Structure

1-benzyl-1-azas...

3-(3-hydroxypropyl)cyclohex-2-en-1-one Structure

3-(3-hydroxypro...

~%

1-benzyl-1-azaspiro[4.5]dec-6-ene Structure

1-benzyl-1-azas...

3-(3-hydroxycyclohex-1-en-1-yl)propyl 4-methylbenzenesulfonate Structure

3-(3-hydroxycyc...

~%

1-benzyl-1-azaspiro[4.5]dec-6-ene Structure

1-benzyl-1-azas...

3-(3-oxocyclohex-1-en-1-yl)propyl 4-methylbenzenesulfonate Structure

3-(3-oxocyclohe...

~%

1-benzyl-1-azaspiro[4.5]dec-6-ene Structure

1-benzyl-1-azas...

3-(3-(tosyloxy)propyl)cyclohex-2-en-1-yl acetate Structure

3-(3-(tosyloxy)...

~%

1-benzyl-1-azaspiro[4.5]dec-6-ene Structure

1-benzyl-1-azas...

3-(3-(benzylamino)propyl)cyclopent-2-en-1-yl acetate Structure

3-(3-(benzylami...

~98%

1-benzyl-1-azaspiro[4.4]non-8-ene Structure

1-benzyl-1-azas...

3-(3'-hydroxypropyl)-2-cyclopenten-1-one Structure

3-(3'-hydroxypr...

~%

1-benzyl-1-azaspiro[4.4]non-8-ene Structure

1-benzyl-1-azas...

N/A Structure

~%

1-benzyl-1-azaspiro[4.4]non-8-ene Structure

1-benzyl-1-azas...

3-(3-oxocyclopent-1-en-1-yl)propyl 4-methylbenzenesulfonate Structure

3-(3-oxocyclope...

~%

1-benzyl-1-azaspiro[4.4]non-8-ene Structure

1-benzyl-1-azas...

acetic acid 3-[3-(toluene-4-sulfonyloxy)-propyl]-cyclopent-2-enyl ester Structure

acetic acid 3-[...

~%

1-benzyl-1-azaspiro[4.4]non-8-ene Structure

1-benzyl-1-azas...

N/A Structure

~97%

6-benzyl-6-azaspiro[4.5]dec-3-ene Structure

6-benzyl-6-azas...

3-(4-hydroxybutyl)cyclopent-2-enone Structure

3-(4-hydroxybut...

~%

6-benzyl-6-azaspiro[4.5]dec-3-ene Structure

6-benzyl-6-azas...

N/A Structure

~%

6-benzyl-6-azaspiro[4.5]dec-3-ene Structure

6-benzyl-6-azas...

4-(3-Oxocyclopent-1-enyl)butyl toluene-4-sulfonate Structure

4-(3-Oxocyclope...

~%

6-benzyl-6-azaspiro[4.5]dec-3-ene Structure

6-benzyl-6-azas...

3-(4-(tosyloxy)butyl)cyclopent-2-en-1-yl acetate Structure

3-(4-(tosyloxy)...

~%

6-benzyl-6-azaspiro[4.5]dec-3-ene Structure

6-benzyl-6-azas...