A series of novel N, O-psiconucleosides has been prepared in both enantiomeric forms by resolution of an advanced racemic synthetic intermediate using (R)-N-phenylpantolactam as a chiral resolution agent. The absolute configuration of all of these compounds has been unequivocally established by chemical correlation with the novel (R)-or (S)-1-methyl-5- phenylpyrrolidine-2, 3-dione, prepared from the known (R)-and (S)-1-methyl-5- ...
