RNA is a key player in many cellular processes and in viral infection, and is therefore an attractive target in drug discovery.[1] The clinical utility of antibiotic drugs that target the bacterial ribosome has demonstrated that RNA can indeed be a relevant target.[2] Among other druggable RNA targets, functional sites within the genomic RNA of HIV-1, such as the transactivation-responsive element (TAR), the Rev-responsive element (RRE), or the ...