A glyceride derivative of chlorambucil (2), 1, 3-dipalmitoyl-2-[4-[bis (2-~ hloroethyl) amino] benzenebutanoyl] glycerol (l), was synthesized and tested as an orally administrable antineoplastic drug endowed with lymphotropic properties. A significantly higher efficacy (increased life span) and a reduced toxicity of 1, relative to 2, were apparent when both compounds given per os were evaluated against P388 leukemia subcutaneously ...
![γ-[p-N-Di(2-chloroethyl)aminophenyl]butyryl chloride Structure](https://image.chemsrc.com/caspic/239/17981-81-6.png)