Uncatalyzed reaction of phenols and naphthols with methyl cinnamates. A simple synthesis of 4-arylchroman-2-ones and 1-arylbenzo [f] chroman-3-ones

G Speranza, A Di Meo, S Zanzola, G Fontana…

Index: Speranza, Giovanna; Di Meo, Antonella; Zanzola, Simona; Fontana, Gabriele; Manitto, Paolo Synthesis, 1997 , # 8 p. 931 - 936

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Citation Number: 12

Abstract

The 4-arylchroman-2-one system (cf. 1) is of synthetic interest because it is present in a number of natural molecules, such as 4-aryl-3, 4-dihydrocoumarins (neoﬁavono-ids), 1* 2 complex ﬂavonoids, 3 eg calomelanols B (1 a) and C (1 b), 4 and 1-arylbenzo [f] chroman-3- ones. 5

~55%

7-Hydroxy-4-(4-methoxyphenyl)-3, 4-dihydrocoumarin

[Rajalakshmi; Jain, Niveta; Deepthi; Krishnamurthy; Pattabhi, Vasantha Acta Crystallographica Section C: Crystal Structure Communications, 1999 , vol. 55, # 5 p. 813 - 815]

Synthetic and novel biocatalytic resolution studies on (±)-5...

[Singh, Ishwar; Prasad, Ashok K.; Sharma, Ajendra K.; Saxena, Rajendra K.; Olsen, Carl E.; Cholli, Ashok L.; Samuelson, Lynne A.; Kumar, Jayant; Watterson, Arthur C.; Parmar, Virinder S. Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 4 p. 529 - 538]