Synthesis, antimicrobial and insecticidal activity of some 4H-1, 2, 4 triazole derivatives

N Gautam, OP Chourasia

Index: Gautam, Nidhi; Chourasia Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010 , vol. 49, # 7 p. 956 - 959

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Citation Number: 12

Abstract

Abstract: 1-(Substituted benzylidene) semicarbazide has been used as a precursor to synthesize some important biologically active 3-substituted phenyl, 4H-1, 2, 4 triazole derivatives. Reaction of ethanolic solution of schiff's base of substituted aromatic aldehyde 1 with ethanolic solution of FeCl 3. 6H 2 O (1 mole FeCl 3. 6H 2 O in 10 mL ethanol) yields the 4H-1, 2, 4 triazole-3-derivative 2. Several derivatives have been synthesized and ...