Conditions for the selective conversion of quaternary 3-anilino-1, 5-dimethylpyrazolium salts into 3-anilino-1, 5-dimethylpyrazole

IB Dzvinchuk, SA Kartashov, AV Vypirailenko…

Index: Dzvinchuk; Kartashov; Vypirailenko; Doller; Lozinskii Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 5 p. 570 - 574

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Abstract

Abstract The possibility has been studied of converting quaternary 3-anilino-1, 5- dimethylpyrazolium salts into 3-anilino-1, 5-dimethylpyrazole, the first representative of the 1- alkyl-3-arylaminopyrazoles. The dependence of the reaction direction on the nature of the substituent at position 2 has been clarified. The most effective result was obtained with a cyanoethyl substituent. On boiling the initial salt with aqueous ammonia the target product ...