Pyrimidine derivatives. 4. Synthesis and antihypertensive activity of 4-amino-2-(4-cinnamoylpiperazino)-6, 7-dimethoxyquinazoline derivatives

…, S Mizogami, M Hanazuka, S Yamada

Index: Sekiya, Tetsuo; Hiranuma, Hidetoshi; Hata, Shunsuke; Mizogami, Susumu; Hanazuka, Mitsuo; Yamada, Shun-ichi Journal of Medicinal Chemistry, 1983 , vol. 26, # 3 p. 411 - 416

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Citation Number: 13

Abstract

15e H 15f H 2-EtOPh D 33 70-73 A c 15 Hz,, N, 0 2 15g H 4-i-PrOPh D 47 90-94 BC,, H,, NZ 0 2 D 24 205-208 e C c 13 HI 5 BrN 2 0 15i Me Ph C 40 oil Cl, Hl, N, O 16a H 2-Th D 54 107- 113 AC, lHl, N, OS 16b Me 2-Th D 51 oil C, ZHI, NZOS D 33 139-140 C Cl, Hl, NZOS D 63 173-180 e C c 12 HI, N, 0s CllH,, NZO,