Alkyl 2-chloro-1, 2, 2-trifluoroethyl ketones and aryl 1, 2, 2, 2-tetrafluoroethyl ketones were respectively prepared by the Friedel–Crafts acylation of trifluoroethene and by the Grignard arylation of N, N-diethyl-1, 2, 2, 2-tetrafluoropropionamide, a hydrolyzed product of hexafluoropropene–diethylamine adduct. These alkyl and aryl polyfluoroalkyl ketones were subjected to base-induced dehydrohalogenation, and resulting trifluorovinyl ketones were ...
