Microwave-assisted synthesis of 2-aryl (hetaryl)-5-phenylamino-1, 3, 4-thiadiazoles from 5-substituted tetrazoles

YA Efimova, GG Karabanovich, TV Artamonova…

Index: Efimova; Karabanovich; Artamonova; Koldobskii Russian Journal of Organic Chemistry, 2009 , vol. 45, # 4 p. 631 - 632

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Citation Number: 5

Abstract

In the recent years 2-aryl-5-arylamino-1, 3, 4-thiadiazoles have attracted considerable attention due to their intrinsic high biological activity [1]. Compounds of the 2-aryl-5- arylamino-1, 3, 4-thiadiazole series were found to exhibit antimicrobial [2], antituberculous [3], and antiphlogistic properties [4], as well as to inhibit development of some cancer diseases [5]. However, the lack of convenient methods for the preparation of 2, 5- ...