Abstract Reaction of pyridinium phenacylids and their picolinium and isoquinolinium counterparts with substituted benzylideneacetophenones gave a wide variety of 2, 4, 6- triaryl-substituted pyridines which are expected to have some potential biological activities. Ammonium acetate in glacial acetic acid was used as the cyclization agent. The structures of resulting pyridines are supported by nmr and ir spectral data.