(From the Laboratory for Organic Chemistry of the Municipal University of Amsterdam). ... N-Methyl-3-hydroxy-4-pyridone-6-carboxylic acid is produced by the action of methylamine on meconic acid and, by splitting off carbon dioxide, N-methyl-3-hydroxy-4-pyridone is obtained. Similar reactions occur with ethylamine and isopropylamine. By the action of these amines on 3-hydroxy-y-pyrone the corresponding N-alkyl-3-hydroxy-4-pyridones are ...
