Incorporation of ortho-carbaboranyl-N ε-modified L-lysine into neuropeptide Y receptor Y1-and Y2-selective analogues

…, AG Beck-Sickinger, E Hey-Hawkins

Index: Stadlbauer, Sven; Loennecke, Peter; Welzel, Peter; Hey-Hawkins, Evamarie European Journal of Organic Chemistry, 2010 , # 16 p. 3129 - 3139

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Citation Number: 27

Abstract

Nontoxic ortho-carbaborane is one of the most promising structure for boron neutron capture therapy (BNCT). For directed uptake of ortho-carbaborane by tumor cells, receptor-subtype selective neuropeptide Y (NPY) and its derivatives were modified with ortho-carbaborane.