Chemical Communications

Facile construction of highly functionalized 2-pyrrolines via FeCl 3-catalyzed reaction of aziridines with arylalkynes

J Fan, L Gao, Z Wang

Index: Fan, Jinmin; Gao, Linfeng; Wang, Zhiyong Chemical Communications, 2009 , # 33 p. 5021 - 5023

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Citation Number: 36

Abstract

Nitrogen-containing five-membered heterocycles are common structural scaffolds in natural products and pharmaceutical agents. Interest in their chemistry continues unabated due to their usefulness as biologically active agents as well as their utility as key intermediates in the synthesis of numerous natural products and medicinal reagents. 1 Among nitrogen-containing five-membered heterocycles, 2-pyrrolines are rather unusual because of the enamine skeleton. Such ...

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