Tetrahedron letters

A first and general route to naphthylisoquinoline alkaloids: the total synthesis of O-methyl-tetradehydro-triphyophylline

G Bringmann, JR Jansen

Index: Bringmann, Gerhard; Jansen, Johannes R. Tetrahedron Letters, 1984 , vol. 25, # 24 p. 2537 - 2540

Full Text: HTML

Citation Number: 21

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Dedicated to professor Sir Derek HR Barton on the occasion of his 65th birthday. ... The first total synthesis of a naphthylisoquinoline alkaloid is described. The required selective mixed coupling of the alkaloid moieties 2 and 6 is achieved -molecularly by the assistance of a ...

 Related Synthetic Route
N/A Structure

92264-20-5

N/A

~68%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

1,8-dimethoxy-3-methylnaphthalene Structure

22273-57-0

1,8-dimethoxy-3...

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

(1S,3R)-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline Structure

92264-15-8

(1S,3R)-8-metho...

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

1-bromo-2-(bromomethyl)-4,5-dimethoxynaphthalene Structure

92264-14-7

1-bromo-2-(brom...

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

N/A Structure

92264-17-0

N/A

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

8-methoxy-1,3-dimethylisoquinoline hydrobromide Structure

82958-26-7

8-methoxy-1,3-d...

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

N/A Structure

92264-23-8

N/A

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

N/A Structure

92264-18-1

N/A

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

(1S,3R)-2-benzyl-8-((1-bromo-4,5-dimethoxynaphthalen-2-yl)methoxy)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline Structure

92264-19-2

(1S,3R)-2-benzy...

~%

7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-2H-isoquinolin-8-one Structure

68727-50-4

7-(4,5-dimethox...

1,8-dimethoxy-3-methylnaphthalene Structure

22273-57-0

1,8-dimethoxy-3...

~61%

1-bromo-2-(bromomethyl)-4,5-dimethoxynaphthalene Structure

92264-14-7

1-bromo-2-(brom...


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