Thioamides have already been shown to be easily convertible to a variety of types of compounds (eg, amines,'enamines, 2 ketene SN-acetal~,~ amide^,^ etc.) and fully proved to be synthetically potential by the total syntheses of vitamin B125 and indole alkaloids. 6 During the course of our study to explore further versatility of thioamides, lb we have found that a,@-unsaturated thioamides react with organolithium and-magnesium compounds ...
