Reversible Grignard and organolithium reactions

RA Benkeser, MP Siklosi…

Index: Benkeser,R.A. et al. Journal of the American Chemical Society, 1978 , vol. 100, p. 2134 - 2139

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Citation Number: 72

Abstract

Abstract: Numerous examples are given of the reversible addition of allylic-type Grignard and organolithium reagents to a variety of ketone substrates. The role of steric hindrance in these reversible additions is clearly demonstrated. Procedures have been devised for the preparation of isomerically pure a-methallylcarbinols derived from the crotyl organometallic. The ketones which form occasionally when the alkoxides of the a-methallylcarbinols ...