e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis of the farnesyl ether 2, 3, 5-trifluoro-6-hydroxy-4-[(E, E)-3, 7, 11-trimethyldodeca-2, 6, 10-trien-1-yloxy] nitrobenzene, and related compounds containing a …
…, IR Hardcastle, MG Rowlands, RM Grimshaw…
Index: Marriott, Jonathan H.; Moreno Barber, Amelia M.; Hardcastle, Ian R.; Rowlands, Martin G.; Grimshaw, Rachel M.; Neidle, Stephen; Jarman, Michael Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 24 p. 4265 - 4278
After a preliminary modelling study 5 in which certain substituted aryl groups, bearing a hydroxy substituent, were compared with di- or tri-phosphate groups (in relation to selection of possible analogues of guanosine 5′-triphosphate), we synthesised the farnesyl compound 2,3,5-trifluoro -6-hydroxy-4-[(E,E )-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy]nitrobenzene (3a), in which the diphosphate group of farnesyl diphosphate is replaced by a 2,3,6-trifluoro-5-hydroxy-4 ...
