Abstract Methanol and stabilized enolates have been found to add to C-4 of homoallylic amines and sulfides in the presence of lithium tetrachloropalladate to give stable chelated palladium complexes in high yield. These complexes may either be isolated or reduced directly with sodium borohydride, providing a simple new route to ω-functionalized amines and sulfides.
![diethyl 2-[1-(dimethylamino)propan-2-yl]propanedioate Structure](https://image.chemsrc.com/caspic/404/63673-88-1.png)