e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
The Journal of Organic Chemistry
Synthesis and reactivity of benzylic epoxides derived from 1, 2, 3, 9, 10, 10a-hexahydrophenanthrene. Search for a unified mechanism for the ring opening of 2- …
The diastereoisomeric benzylic epoxides 4a and 4b were synthesized, and their ring- opening reactions under acidic conditions were compared with those of the known epoxides 2 and 3. The chemical behavior of 4 more nearly resembles that of 3, thus suggesting that the differences in chemical behavior between 2 and 3 could be ascribed to the different conformational rigidity of the aryl in these systems. The ring opening of 4 forms significant ...
