e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Catalysis Communications
Highly regioselective cyclotrimerization of terminal alkynes catalyzed by Fe (II) complexes bearing 2-(benzimidazolyl)-6-(1-(arylimino) ethyl) pyridines
FeCl2 ligated with 2-(benzimidazolyl)-6-(1-(arylimino) ethyl) pyridine in the presence of zinc powder and zinc iodide could effectively catalyze cyclotrimerization of intermolecular alkynes to afford benzene derivatives in high regioselectivity. The synthetic usefulness of this catalytic system consisting of Fe (II) complex C1, Zn and ZnI2 in acetonitrile was tested with various terminal alkynes. In the cases of using aryl substituted alkynes, the 1, 2, 4- ...