The Journal of Organic Chemistry

Synthesis of substituted pyrroles by intramolecular condensation of a Wittig reagent with the carbonyl group of a tertiary amide

JV Cooney, WE McEwen

Index: Cooney, John V.; McEwen, William E. Journal of Organic Chemistry, 1981 , vol. 46, # 12 p. 2570 - 2573

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Citation Number: 63

Abstract

Isolated yield. Asterisk indicates some of the amine hydrochloride present as catalyst. Diketone dissolved in hot (155" C) aniline (10 min). produced via the diketone. New compound. e Refluxing 22.5 h also gave 50% yield. None of the pyrrole could be No attempt made to prepare compound by Paal-Knorr procedure. the carbonyl group. We have found no reports in the literature of the successful reaction of Wittig reagents with the carbonyl ...