Optimization of inhibitors of the tyrosine kinase EphB4. 2. Cellular potency improvement and binding mode validation by X-ray crystallography

K Lafleur, J Dong, D Huang, A Caflisch…

Index: Journal of Medicinal Chemistry, , vol. 56, # 1 p. 84 - 96

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Citation Number: 11

Abstract

... Journal of Medicinal Chemistry. ... Department of Organic Chemistry and ‡ Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. J. Med. Chem. , 2013, 56 (1), pp 84–96. ...