… Replicase Inhibitors: Base-Catalyzed Synthesis of Protected α-Hydrazino Esters and Selective Aerobic Oxidation with Catalytic Pt/Bi/C for Synthesis of Imidazole-4, 5- …

RK Bowman, AD Brown, JH Cobb…

Index: Cameron, Donald W.; Gan, Chee-Yong; Griffiths, Peter G.; Pattermann, Judy A. Australian Journal of Chemistry, 1998 , vol. 51, # 5 p. 421 - 432

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Citation Number: 7

Abstract

... The Journal of Organic ... In a scale-up to produce prodrug 1 with input of 218 g of bromoacetate 15, the ratio 1/6 (prodrug/parent ... Reaction of the dialdehyde with hydrazine further complicated the chemistry by generating several insoluble oligomeric impurities which could not be ...