e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
… Replicase Inhibitors: Base-Catalyzed Synthesis of Protected α-Hydrazino Esters and Selective Aerobic Oxidation with Catalytic Pt/Bi/C for Synthesis of Imidazole-4, 5- …
RK Bowman, AD Brown, JH Cobb…
Index: Cameron, Donald W.; Gan, Chee-Yong; Griffiths, Peter G.; Pattermann, Judy A. Australian Journal of Chemistry, 1998 , vol. 51, # 5 p. 421 - 432
... The Journal of Organic ... In a scale-up to produce prodrug 1 with input of 218 g of bromoacetate 15, the ratio 1/6 (prodrug/parent ... Reaction of the dialdehyde with hydrazine further complicated the chemistry by generating several insoluble oligomeric impurities which could not be ...