Journal of the American Chemical Society

Biosynthesis of the Nicotiana Alkaloids. X. The Incorporation of Glycerol-2-C14 into the Pyridine Ring of Anabasine

E Leete, AR Friedman

Index: Leete,E.; Friedman,A.R. Journal of the American Chemical Society, 1964 , vol. 86, p. 1224 - 1226

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Citation Number: 12

Abstract

The administration of glycerol-2-C14 to nicotzana glazica plants leads to the formation of radioactive anabasine which has 387, of its activity located in the pyridine ring A systematic degradation is described whereby the distribution of activity around the pyridine ring can be determined The anabasine derived from glycerol-2-CI4 was found to have substantial activity at C-2, C-3, and C-5, with only low activity at C-4 and C-6 These results are ...