Tetrahedron

Regioselective quadruple domino aldolization/aldol condensation/Michael/SN Ar-cyclization: construction of hexacyclic indeno-fused C-nor-D-homo-steroid …

T Chanda, S Chowdhury, BJ Ramulu, S Koley…

Index: Chanda, Tanmoy; Chowdhury, Sushobhan; Ramulu, B. Janaki; Koley, Suvajit; Jones, Raymond C.F.; Singh, Maya Shankar Tetrahedron, 2014 , vol. 70, # 12 p. 2190 - 2194

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Citation Number: 5

Abstract

Abstract An operationally simple and highly atom-economic anionic quadruple domino reaction sequence for the synthesis of hexacyclic indeno-fused naphthalene/quinoline molecules having structural resemblance with the C-nor-D-homo-steroid nucleus has been developed. Promoter and solvent specificity, regioselectivity and mechanistic details were experimentally established. Catalyst concentration and solvent dependent switching of ...

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