Unsymmetrical 1, 3-diaminobenzenes and diaminopyridines were efficiently prepared by reaction of 3-chloroanilines and chloroaminopyridines with amines via a nickel-catalysed amination. The Ni/2, 2′-bipyridine catalyst is also effective for the sequential amination of aryl trichlorides. After a first selective monoamination of 1, 3, 5-trichlorobenzene, the obtained 3, 5-dichloroanilines were subsequently transformed into novel and ...
