e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Asymmetric codimerization of cyclohexa-1, 3-diene with ethylene catalysed by chiral aminophosphine-nickel complexes
G Buono, G Peiffer, A Mortreux, F Petit
Index: Buono, Gerard; Peiffer, Gilbert; Mortreux, Andre; Petit, Francis Journal of the Chemical Society, Chemical Communications, 1980 , # 20 p. 937 - 939
The asymmetric codimerization of cyclohexa-1, 3-diene with ethylene is catalysed by the Ni (cyclo-octa-1, 5-diene)–AlEtCl–L system where L are chiral aminophosphines; optimization of this catalytic system (–70° C; L/Ni= 10) gives (+)-()-3-vinylcyclohexene with 73· 5% optical purity in 87% chemical yield when (–)-()--me