It1 the absence of any added catalyst acetylene reacts with aminoalcohols, RNH (CRz),, OH, where R is H or an alkyl group and n is 2 or 3, at pressures of 400-500 psi and temperatures of 100 to ZOO”, to form 2-methyloxazolidines (I, n= 2) and 2-methyltetrahydro-l, 3-oxazines (I, n= 3). Owing to the instability of these products at reaction temperatures, the reactions are best carried out to 10-30Oj, conversions. Yields based on unrecovered aminoalcohol then ...
