Tetrahedron letters

New geiparvarin analogues from 7-(2-oxoethoxy) coumarins as efficient in vitro antitumoral agents

…, B Cosimelli, G Viola, D Vedaldi, F Dall'Acqua

Index: Chimichi, Stefano; Boccalini, Marco; Cosimelli, Barbara; Viola, Giampietro; Vedaldi, Daniela; Dall'Acqua, Francesco Tetrahedron Letters, 2002 , vol. 43, # 42 p. 7473 - 7476

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Citation Number: 55

Abstract

A new class of compounds analogues of geiparvarin is described: aldolic condensation of 3 (2H)-furanones and 7-(2-oxoethoxy) coumarins followed by a very efficient dehydration protocol led to the title compounds which show good antitumoral activity against several human cell lines.