Synthetic Communications

Mild and Efficient Chemoselective Tetrahydropyranylation of Alcohols Using Brønsted Acidic Ionic Liquid as Catalyst Under Solvent-Free Conditions

AR Hajipour, Z Nasresfahani

Index: Hajipour, Abdol R.; Nasresfahani, Zahra Synthetic Communications, 2012 , vol. 42, # 13 p. 1995 - 2006

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Citation Number: 8

Abstract

Tetrahydropyranyl (THP) ether is one of the most versatile protecting groups for alcohols in modern organic syntheses because it is stable under a variety of reaction conditions such as alkaline media and toward Grignard and alkyl lithium reagents, oxidative reagents, as well as alkylating and acylating reagents. [ 1 1. (a) Green , TW ; Wuts , PGM Protective Groups in Organic Synthesis; , 3rd ed. ; John Wiley : New York , 1999 , p. 306 ; (b) Caine , D. ; Deutsch , H. ...