The wide applications of macrocycles emphasise their efficacy in various fields such as molecular recognition,1 metal extraction and separation,2 medical diagnostics3 and drug delivery systems,4 chemical synthesis,5 polymer chemistry6 and in food science.7 The macrocycles also play a vital role in molecular architecture and topology8 and more recently in the field of nano-chemistry.9 Chiral cyclophanes1,10 have substantial significance in host–guest ...