Synthesis, characterization, antimicrobial and single crystal X-ray crystallographic studies of some new sulfonyl, 4-chloro phenoxy benzene and dibenzoazepine …

…, MV Tejesvi, G Sarala, SL Gaonkar, S Naveen…

Index: Priya; Nanjunda Swamy; Tejesvi; Basappa; Sarala; Gaonkar; Naveen; Shashidhara Prasad; Rangappa European Journal of Medicinal Chemistry, 2006 , vol. 41, # 11 p. 1262 - 1270

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Citation Number: 11

Abstract

A new class of benzamide derivatives 3a (I–VI) and 3b (I–VI), bearing different bioactive moieties were synthesized and evaluated for their efficacy as antimicrobials in vitro. Compounds 3bVI, 3aII, 3aV, 3bIII, 3aVI, 3bII showed significant antibacterial activity and 3bIII, 3bII, 3aIV, 3bV, 3bVI, 3aI exhibit significant antifungal activity. The title compounds are characterized by spectral and elemental analysis. Compounds 2-methoxy-N-[4-(thiazol-2- ...