Di-and Tri-1-(1-naphthyl) ethylamino-Substituted 1, 3, 5-Triazine Derivatives: A New Class of Versatile Chiral Auxiliaries for NMR Spectroscopy

G Uccello-Barretta, A Iuliano, E Franchi…

Index: Uccello-Barretta, Gloria; Iuliano, Anna; Franchi, Emanuela; Balzano, Federica; Salvadori, Piero Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9197 - 9203

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Citation Number: 13

Abstract

2-Chloro-4, 6-bis [(R)-1-(1-naphthyl) ethylamino]-1, 3, 5-triazine, 2, 4, 6-tris [(R)-1-(1- naphthyl) ethylamino]-1, 3, 5-triazine, and 2, 4-bis [(R)-1-(1-naphthyl) ethylamino]-6-[(S)-1-(1- naphthyl) ethylamino]-1, 3, 5-triazine have been synthesized, and their efficiency and versatility as chiral solvating agents for the determination by NMR of the enantiomeric composition of derivatized or underivatized chiral compounds have been demonstrated.