Tetrahedron

Ring opening of the epoxide moiety of (2S, 3S, 4S)-4-amino-2, 3-epoxy-1-alkanol and its derivatives: A key role of Ti (Oi-Pr) 4 as a mild catalyst

H Urabe, Y Aoyama, F Sato

Index: Urabe, Hirokazu; Aoyama, Yoshiaki; Sato, Fumie Tetrahedron, 1992 , vol. 48, # 27 p. 5639 - 5646

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Citation Number: 24

Abstract

(2S, 3S, 4S)-4-Amino-2, 3-epoxy-1-alkanol gave 4-amino-1, 3-alkanediol or 3, 4-imino-1, 2- alkanediol with Dibal or Ti (Oi-Pr) 4 respectively and, after introduction of Boc group to its amino group, afforded a 4-amino-1, 2, 3-alkanetriol derivative under the influence of Ti (Oi- Pr) 4.