An efficient method for the synthesis of 1-chlorophenazines has been established. It is based on the use of 3, 6, 6-trichloro-2-hydroxy-2-cyclohexen-1-one as a synthetic equivalent of 3-chloro-1, 2-benzoquinone. The intermediate was prepared in near quantitative yield by electroreductive monodechlorination of 3, 3, 6, 6-tetrachloro-1, 2-cyclohexanedione, which is an inexpensive and easily available starting material. Efficient reactions of with primary ...
