Tetrahedron

Access to a new family of medium ring aromatic lactones

E Métay, E Léonel, S Condon, JY Nédélec

Index: Metay, Estelle; Leonel, Eric; Condon, Sylvie; Nedelec, Jean-Yves Tetrahedron, 2006 , vol. 62, # 36 p. 8515 - 8524

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Citation Number: 14

Abstract

We report a new method for preparation of hydroxyacids as precursors of benzolactones using a simple and an efficient electrochemical step. This gives in only four steps six-to eleven-membered lactones with high isolated yields from conveniently substituted aryl bromides. The lactonisation was performed according to the Yamamoto's process.