e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron letters

Furaquinocins AG: relative and absolute stereochemistry

PG Dormer, AB Smith, S Funayama, S Omura

Index: Dormer, Peter G.; Smith, Amos B.; Funayama, Shinji; Omura, Satoshi Tetrahedron Letters, 1992 , vol. 33, # 13 p. 1717 - 1720

Full Text: HTML

Citation Number: 12

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The complete relative and absolute stereochemistry of furaquinocins AG, a family of cytotoxic antibiotics, have been assigned via a combination of X-ray crystallography, NMR analysis of the derived Mosher esters, and chemical correlation. ... The complete relative and ...

(2R,3S)-4-hydroxy-3-((R,Z)-1-hydroxy-4-methyl-5-(phenylthio)pent-3-en-1-yl)-7-methoxy-2,3,8-trimethyl-2,3-dihydronaphtho[1,2-b]furan-6,9-dione Structure

(2R,3S)-4-hydro...

~19%

furaquinocin D Structure

furaquinocin A Structure

~%

furaquinocin D Structure

N/A Structure

~41%

furaquinocin E Structure

(2R,3S)-3-((R,E)-5-(benzoyloxy)-1-hydroxy-4-methylpent-3-en-1-yl)-7-methoxy-2,3,8-trimethyl-6,9-dioxo-2,3,6,9-tetrahydronaphtho[1,2-b]furan-4-yl benzoate Structure

(2R,3S)-3-((R,E...

~%

furaquinocin E Structure

furaquinocin B Structure

~%

furaquinocin E Structure

furaquinocin A Structure

~33%

N/A Structure

furaquinocin G Structure

furaquinocin C Structure

~19%

furaquinocin F Structure

Total synthesis of the furaquinocins

[Saito, Takeshi; Suzuki, Takao; Morimoto, Munetsugu; Akiyama, Chikako; Ochiai, Takashi; Takeuchi, Kazuhiro; Matsumoto, Takashi; Suzuki, Keisuke Journal of the American Chemical Society, 1998 , vol. 120, # 45 p. 11633 - 11644]

Total synthesis of the furaquinocins

[Saito, Takeshi; Suzuki, Takao; Morimoto, Munetsugu; Akiyama, Chikako; Ochiai, Takashi; Takeuchi, Kazuhiro; Matsumoto, Takashi; Suzuki, Keisuke Journal of the American Chemical Society, 1998 , vol. 120, # 45 p. 11633 - 11644]

Total synthesis of the furaquinocins

[Saito, Takeshi; Suzuki, Takao; Morimoto, Munetsugu; Akiyama, Chikako; Ochiai, Takashi; Takeuchi, Kazuhiro; Matsumoto, Takashi; Suzuki, Keisuke Journal of the American Chemical Society, 1998 , vol. 120, # 45 p. 11633 - 11644]

Total synthesis of the furaquinocins

[Saito, Takeshi; Suzuki, Takao; Morimoto, Munetsugu; Akiyama, Chikako; Ochiai, Takashi; Takeuchi, Kazuhiro; Matsumoto, Takashi; Suzuki, Keisuke Journal of the American Chemical Society, 1998 , vol. 120, # 45 p. 11633 - 11644]

Total synthesis of the furaquinocins

[Saito, Takeshi; Suzuki, Takao; Morimoto, Munetsugu; Akiyama, Chikako; Ochiai, Takashi; Takeuchi, Kazuhiro; Matsumoto, Takashi; Suzuki, Keisuke Journal of the American Chemical Society, 1998 , vol. 120, # 45 p. 11633 - 11644]