Total synthesis of marine mercaptohistidines: ovothiols A, B, and C

…, F Ruan, A Spaltenstein, PB Hopkins

Index: Holler, Tod P.; Ruan, Fuqiang; Spaltenstein, Andreas; Hopkins, Paul B. Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4570 - 4575

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Citation Number: 40

Abstract

The ovothiols (1) are a family of 4-mercaptohistidine derivatives that are abundant in the eggs of marine invertebrates.'Unlike the 2-mercaptohistidine derivative ergothioneine, which has been known since early in this century, the ovothiols were first isolated only in the late 1970s. Obtained first as a chemical degradation product