Synthesis and Glutathione Peroxidase??Like Activities of Isoselenazolines

VP Singh, HB Singh, RJ Butcher

Index: Singh, Vijay P.; Singh, Harkesh B.; Butcher, Ray J. European Journal of Organic Chemistry, 2011 , # 28 p. 5485 - 5497

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Citation Number: 13

Abstract

Abstract The aromatic nucleophilic substitution (SN Ar) reactions of N-(2-bromo-3- nitrobenzyl) aniline (18), N-(2-bromo-3-nitrobenzyl)-4-methylaniline (19) and N-(2-bromo-3- nitrobenzyl)-4-nitroaniline (20) with [nBuSeNa] afford N-[2-(butylselanyl)-3-nitrobenzyl] aniline (21), N-[2-(butylselanyl)-3-nitrobenzyl]-4-methylaniline (22) and N-[2-(butylselanyl)-3- nitrobenzyl]-4-nitroaniline (23), respectively. The bromination of 21 results in the formation ...