The plasmalogens were first isolated by Feulgen and Ber~ in,~ in 1939, from horse muscle following T'1'g orous alkaline hydrolysis of the ester phosphatides. It appeared that the aliphatic aldehyde formed an acetal bond with the glycerol skeleton, and that the phosphorus and nitrogen base (ethanolamine) was attached by ester bonding to the third hydroxy group in glycerol.
[Doren, Henk A. van; Geest, Ralph van der; Kellogg, Richard M.; Wynberg, Hans Recueil des Travaux Chimiques des Pays-Bas, 1990 , vol. 109, # 3 p. 197 - 203]
![[2-(1-bromo-octyl)-[1,3]dioxolan-4-yl]-methanol Structure](https://image.chemsrc.com/caspic/078/92039-13-9.png)
