Switchable Palladium-Catalyst Reaction of Bromomethyl Sulfoxides, CO, and N-Nucleophiles: Aminocarbonylation at Csp3 versus Oxidative Carbonylation of Amines

…, M Medio-Simón, G Asensio

Index: Medio-Simon, Mercedes; Mollar, Cristian; Rodriguez, Nuria; Asensio, Gregorio Organic Letters, 2005 , vol. 7, # 21 p. 4669 - 4672

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Citation Number: 10

Abstract

The palladium-catalyzed reaction of α-bromomethyl sulfoxides, carbon monoxide, and N- nucleophiles follows different reaction pathways according to the catalytic system and the reaction conditions. The Pd-xantphos catalyst affords high yields of α-sulfinyl amides by an