Ruthenium (II) complexes of 4-nitroimidazoles: their characterization, solution chemistry, and radiosensitizing activity

…, PKH Chan, DC Frost, BR James…

Index: Chan, Peter K. L.; Chan, Paul K. H.; Frost, David C.; James, Brian R.; Skov, Kirsten A. Canadian Journal of Chemistry, 1988 , vol. 66, p. 117 - 122

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Citation Number: 42

Abstract

A series of ruthenium (II) complexes of formulation RuCl2 (dmso) 2L n, where dmso= S- bonded dimethylsulfoxide, L is a 4-nitroimidazole derivative, and n= 1 or 2, have been synthesized and characterized by spectroscopic methods, particularly 1H nmr and X-ray photoelectron spectroscopy. With L= 4-nitroimidazole itself (4-NO2Im), RSU-1170,-3083 or- 3100, n= 2 and the six-coordinate complexes are considered to be of cis, cis, cis-geometry ...