Versatile Route to Functionalized 1 H-2-Benzothiopyrans and 1 H-2-Naphthothiopyrans by Electrophilic Cyclization of Bis (arylmethylthio) acetylenes: 2-Benzo-and 2- …

TR Klein, M Bergemann, NAM Yehia…

Index: Klein; Bergemann; Yehia; Fanghanel Journal of Organic Chemistry, 1998 , vol. 63, # 14 p. 4626 - 4631

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Citation Number: 19

Abstract

Substituted 1 H-2-benzothiopyrans find applications as pharmaceutically active compounds or synthons for more complex sulfur heterocycles. However, restricted variability in their synthesis limits the application for research or industrial purposes. To develop a direct and fast route to substituted and functionalized 1 H-2-benzothiopyrans, we investigated the ring closure of symmetrical bis (arylmethylthio) acetylenes with iodine monochloride or ...