Synthesis and Biological Evaluation of Some Novel [4-(1H-Benzoimidazol-2-yl)-thiazol-2-yl]-benzylidene-amines and N-[4-(1H-Benzoimidazol-2-yl)-thiazol-2-yl] …

RVR Mekala, RR Danda, H Gadegoni

Index: Mekala, Raghu Vardhan Reddy; Danda, Ravinder Reddy; Gadegoni, Hemalatha Journal of the Korean Chemical Society, 2013 , vol. 57, # 1 p. 94 - 98

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Abstract

ABSTRACT. A new family of thiazole heterocycles, namely [4-(1H-benzoimidazol-2-yl)- thiazol-2-yl]-benzylidene-amines has been synthesized by the condensation of 4-(1H- Benzoimidazol-2-yl)-thiazol-2-ylamine with various aromatic aldehydes and N-[4-(1H- benzoimidazol-2-yl)-thiazol-2-yl]-N'-benzylidene-hydrazines through the cyclization of 1-(1H- benzoimidazol-2-yl)-2-bromo-ethanone with arylthiosemicarbazones. The target ...