In continuation of the previous investigations into the pharmacological activity of aroylpyruvic acid amides [1], we have synthesized a series of new compounds &this class, con- taining [3-arylhydrazone fragments, and assessed their activity in comparison with that of the other reported amides [2]. Interactions of 1-phenyl-3-aroyl-4,5-dihydro-4,5-pyra- zolodiones (I) with primary aromatic amines and secondary cyclic amines (morpholine and piperidine) led to the ...